5-Amino 1MQ

Description

5-Amino-1MQ is a small molecule that has been studied for its role in modulating cellular metabolism through the inhibition of the enzyme nicotinamide N-methyltransferase (NNMT). NNMT is highly active in adipose tissue and is involved in regulating energy balance and metabolic efficiency.

In preclinical research, the inhibition of NNMT by 5-Amino-1MQ has been associated with increased levels of NAD⁺ (nicotinamide adenine dinucleotide), a coenzyme central to cellular energy production and metabolic function. This increase in NAD⁺ has been linked to the activation of SIRT1, a gene often associated with metabolic health, cellular repair, and longevity pathways.

Animal studies have explored the potential effects of 5-Amino-1MQ on body composition, with some models showing reductions in body mass without changes in caloric intake. Additional research has examined its possible impact on adipocyte (fat cell) regulation, suggesting a role in the modulation of fat storage and tissue remodeling.

This compound is intended strictly for laboratory research use only and is not approved for human or veterinary use.

5-Amino 1MQ Research

5-Amino-1MQ is a small molecule that has gained attention in preclinical research for its role in modulating cellular energy and metabolism. It works by inhibiting nicotinamide N-methyltransferase (NNMT), an enzyme known to regulate metabolic activity, particularly within adipose (fat) tissue.

Key areas of research interest include:

• NAD⁺ Regulation: Blocking NNMT has been shown to increase levels of NAD⁺ (nicotinamide adenine dinucleotide), a coenzyme involved in cellular respiration and energy production. Elevated NAD⁺ levels are linked to improved mitochondrial function and enhanced metabolic efficiency in experimental models.
• SIRT1 Activation: In some studies, 5-Amino-1MQ has been associated with the upregulation of SIRT1, a gene connected to cellular repair, metabolism, and longevity-related pathways.
• Fat Cell Response: Research in animal models suggests that NNMT inhibition may reduce fat cell size and influence fat storage, contributing to changes in body composition without alterations in food intake.
• Metabolic Health: Early-stage studies are exploring whether 5-Amino-1MQ has potential in models of metabolic dysfunction, including insulin sensitivity and adipose tissue regulation.

These findings are derived from animal and in vitro studies and remain under active investigation.
5-Amino-1MQ is provided strictly for laboratory research use only and is not intended for human or veterinary use.